Brett Taylor, MD - Spinal Fusion in St. Louis MOThe Effect of Nicotine On Spinal Fusion. The animal model established a direct relationship between the development of a nonunion in the presence of systemic nicotine. Nevertheless, nicotine clearly inhibited the incorporation of autologous bone graft into a spine fusion mass. Previous studies by our group showed that nicotine delivered via a transdermal nicotine patch significantly enhanced posterior spinal fusion rates in rabbits. Nicotine transdermal patches provide a steady serum level; there.
Nonunion of spine fusions is an enormous clinical problem with no easy solution. Because tobacco products contain nicotine, it is justifiable to insist that patients stop smoking or using tobacco products before undergoing spinal fusion. Quit Smoking to Improve the Outcome of Your Spinal Fusion Surgery. Submitted by Nicola V. Nicotine also decreases your body's blood circulation. Stopping nicotine exposure before surgery. Chronic nicotine exposure was shown to decrease spinal fusion rates. Discontinuing nicotine before surgery.
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